David G. Olarsch, N.D.
Naturopathic Doctor
“The doctor of the future will give no medicine, but will interest his patient in the care of the human frame, in diet and in the cause and prevention of disease.”
Thomas A. Edison

Stress Calm Px


Price: $0.00

SKU: 1057
Size: 75 Vegi-Caps

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Serving Size: 2 vegetarian capsules
Ingredients per serving:
Ashwagandha root (Withania somnifera) extract 10:1    1000 mg
Pulsatilla root (Pulsatilla chinensis) extract 4:1~    200 mg
Catnip herb (Nepeta cataria)**    100 mg
Lavender flower (Lavandula angustifolia)**    10 mg
Indian Snakeroot (Rauwolfia serpentina) extract 10:1    6 mg
**Certified Organic
~Wildcrafted

Suggested Use:
1-2 capsules twice daily.
Should only be taken under the care of a licensed healthcare practitioner.



Overview:
The name says it all. A powerful anti-stress formula that restores vitality ravaged by stress. Also use to support adrenal gland health.
Another WTSmed professional supplement.

StressCalm Px is a very effective formula for alleviating symptoms of occasional stress and supporting the health of the nervous system in its ability to handle demanding stressors. The herbs in this well-crafted formula maintains stress tolerance by supporting adrenal and central nervous system functions.

The main herb in this formula, Ashwagandha or Withania is an adaptogenic herb which has been shown to support adrenal function and improve the ability to deal with occasional stress. Ashwagandha has been shown to maintain GABA receptors in the brain to provide a calming and relaxing effect. The species name somnifera hints at the long standing reputation of this herb to improve the quality of sleep.

Catnip and lavender also maintain calmness and relaxation and are classic herbs for nervous system support. Rauwolfia or Indian Snake root has been employed for centuries in India for maintaining support for the parasympathetic system.



In Depth:
From the WTSmed website:

Health concerns relevant to this product*
Chronic Stress
High Cortisol
Adrenal Resistance
Anxious mood
Nervousness
High Blood Pressure
Insomnia



Supporting Research

Stress/Anxiety

Adrenal Regulation
Ashwagandha is an adaptogenic herb which has been shown to help regulate adrenal function. It is believed that when there is an excess of certain hormones, such as cortisol, the plant-based hormone precursor occupies cell membrane receptor sites so the actual hormone cannot attach and exert its effect. Animal trials of Ashwagandha have shown a decrease in the number and severity of a number of stress induced symptoms including acid indigestion, inhibition of male sexual behavior, inability to retain learned tasks, and immune suppression.

Reduced Anxiety
Catnip (Nepeta cataria) is a mild sedative. It has been shown to contain Nepetalactone, a compound similar to a class of substances called valepotriates, known for their sedative properties. Pulsatilla or pasque flower herb contains potent glycosides such as ranunculin, and is used frequently in Europe for its anxiolytic properties. Rauwolfia has been employed for centuries for the relief of various central nervous system disorders including nervousness, irritability, and insomnia. It is well accepted that the pharmacological effects of Rauwolfia are due to its alkaloids, especially reserpine. Rauwolfia and its major alkaloids have been shown to deplete stores of the excitatory neurotransmitters known as catecholamines (epinephrine and norepinephrine) from peripheral sites and the brain.

Ashwagandha
(withania somnifera)

Chronic stress
Ashwagandha is considered to be an adaptogen, facilitating the ability to withstand stress and supporting the immune system. Withania somnifera and Panax ginseng extracts were compared for their ability to attenuate some effects of chronic stress (CS). Both botanicals were able to decrease the number and severity of CS-induced ulcers, reverse CS-induced inhibition of male sexual behavior, and inhibit the adverse effects of CS on retention of learned tasks. Both botanicals also reversed CS-induced immuno-suppression. (1)

Cardiovascular Protection
Hypoglycemic, diuretic, and hypo-cholesterolemic effects of ashwagandha root were assessed in human subjects, in which six type 2 diabetes mellitus subjects and six hyper-cholesterolemic subjects were treated with a powder extract for 30 days. A decrease in blood glucose comparable to that of an oral hypoglycemic drug was observed. Significant increases in urine sodium, urine volume, and decreases in serum cholesterol, triglycerides, and low-density lipoproteins were also seen. (2)

Improved Thyroid Function
An aqueous extract of dried Withania root was given to mice via gastric intubation at a dose of 1.4 g/kg body weight daily for 20 days. Serum was collected at the end of the 20 day period and analyzed for T3 and T4 concentrations, and lipid peroxidation was measured in liver homogenate via antioxidant enzyme activity. Significant increases in serum T4 were observed, indicating the plant has a stimulatory effect at the glandular level. No changes in T3 levels were observed. Withania extract significantly decreased lipid peroxidation and significantly increased antioxidant activity, promoting scavenging of free radicals that can cause cellular damage. These results indicate ashwaghanda is a useful botanical in treating low thyroid function. (3)

References:
1. Alternative Medicine Review, Volume 9, Number 2; 2004 "Monograph: Withania somnifera".

2. Bhattarcharya SK, Muruganandam AV. Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress. Pharmacol Biochem Behav 2003;75:547-555.

3. Harney JW, Barofsky IM, Leary JD. Behavioral and toxicological studies of cyclopentanoid monoterpenes from Nepeta cataria. Lloydia 1978 Jul-Aug; 41(4):367-74.

4. Rand MJ, Jurevics H. The pharmacology of Rauwolfia alkaloids. In: Gross F, ed. Antihypertensive agents. New York, Springer-Verlag, 1977:77-159.


* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.


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